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woman sad blue red hair painting portrait art expression emotion melancholy sorrow grief despair hopelessness anguish torment misery unhappiness depression mental health illness disease suffer pain hurt injury damage harm abuse neglect abandonment loneliness isolation alienation rejection betrayal heartbreak loss death grief mourning sorrow sadness melancholy despair hopelessness anguish torment misery unhappiness depression mental health illness disease suffer pain hurt injury damage harm abuse neglect abandonment loneliness isolation alienation rejection betrayal heartbreak loss death